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Case Studies

Case Studies

CaseStudy-Dr. Manasa Nandimandalam
9. April 2026

Case Study I Intestine-on-chip to study infection and inflammation dynamics

We had the opportunity to speak to Dr. Manasa Nandimandalam from the Hannover Medical School. She developed an advanced in vitro model on-chip to simulate intestinal environments for comprehensive studies of infection and inflammation dynamics.
CaseStudy-ValentinWegner
9. April 2026

Case Study I Intestinal adenocarcinoma-on-chip model

We had the opportunity to speak to Valentin Wegner from the University Hospital Jena in Germany. He works on the modulation of CAR T-cell efficacy by short-chain fatty acids in a ROR1-positive intestinal adenocarcinoma-on-chip model.
CaseStudy-Inês Silva
9. April 2026

Case Study I Microphysiological approach to study dopaminergic injury and inflammation interplay in Parkinson’s disease

We had the opportunity to speak to Inês Silva from the NOVA Institute for Medical Systems Biology in Portugal. She has developed a microphysiological approach to study dopaminergic injury and inflammation interplay in Parkinson’s disease.
Daniela Marques
9. April 2026

Case Study I Microglia crosstalk MPS model of the blood-brain barrier

We had the opportunity to speak Daniela Marques from the NOVA Institute for Medical Systems Biology in Portugal. She has developed a microglia crosstalk MPS model of the blood-brain barrier to disclose polyphenol metabolites potential.
CaseStudy-AdrianFeile
9. April 2026

Case Study I Vibrio cholerae in a 3D-intestine-on-chip infection model

We had the opportunity to speak Adrian Feile from the University Hospital Jena in Germany. He has shown that DPO (3,5-dimethylpyrazin-2-ol)-dependent quorum sensing modulates biofilm behavior of Vibrio cholerae in a 3D-intestine-on-chip infection model.
CaseStudy-MariaWarschinke
9. April 2026

Case Study I Intestine-on-chip that enables Clostridioides difficile infection in a hypoxic microenvironment

We had the opportunity to speak to Maria Warschinke from the University Hospital Jena in Germany. She is working on an immunocompetent intestine-on-chip that enables Clostridioides difficile infection in a hypoxic microenvironment.
CaseStudy-NicoleEngert
8. April 2026

Case Study I Stem cell-derived gut-on-chip model to elucidate human norovirus infections

We had the opportunity to speak to Dr. Nicole Engert from University Hospital Jena in Germany. She is working on a stem cell-derived gut-on-chip technology to elucidate human norovirus infections.