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Drug Development

Drug development

Introduction to drug discovery and drug development

In this blog we will provide you with an introduction to the drug development process from target validation to post-market surveillance to give you a better understanding on how new drugs are being developed.

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Liver-on-a-chip – Revolutionizing assessment of drug-induced liver injury

Summary of our work that established a human liver microphysiological model as an in vitro platform for the evaluation of drug-induced liver injury, published in Nature Scientific Reports. This case study sheds light on the effects of the known hepatotoxic antibiotic trovafloxacin and the commonly used analog levofloxacin on human liver tissue, using an innovative chip-based liver model.