Multi-organ-on-chip model for improving drug safety during pregnancy
May 22, 2025 | online | 16–17 pm (CEST)
Webinar by Dynamic42 in cooperation with ESQlabs
Topic: “Multi-organ-on-chip model for improving drug safety during pregnancy“
Please register here.
Ensuring medication safety during pregnancy remains a well-known issue in pharmacology. Despite almost 90% of pregnant women taking medications, only around 10% of approved drugs have been specifically tested for safety in pregnant women. The placental transfer potential of many substances remains unclear, increasing the risk of unexpected side effects.
In a first-of-its-kind collaboration Bayer’s Consumer Health Division, MPSlabs (part of ESQlabs), Dynamic42 GmbH and Placenta Lab of Jena University Hospital have developed an organ-on-chip platform and interactive computational software to understand whether small molecules can cross the blood-placenta-barrier in pregnant women.
Within this webinar:
/ Katja Graf from Dynamic42 will give detailed insight into the development of the intestine-liver-placenta on-chip model
/ Christian Maas will show how digital twin technology accurately captures the pharmacokinetics of the individual on-chip models
/ Both show results for an example of Prednisone as a commonly prescribed corticosteroid during pregnancy
Register below to join the webinar live or receive the recording afterward.