The development of an active substance from its discovery to approval is very time-consuming and costly. Withdrawing a drug in the human clinical phase as well as after approval due to unforeseen side effects is a waste of resources that you do not need and that your stakeholders want to avoid.
Therefore, a reliable in vitro technology that provides you with information on whether your compound will be tolerable or toxic is of high economic and ethical interest. The human in vitro microphysiological models created and offered by Dynamic42 GmbH can address this need. They are composed of a blood vessel structure on the one hand and an organ-specific tissue on the other. The perfusion of the blood vessel compartment allows the formation of an in vivo-like microenvironment. Our ability to perfuse and integrate tissue-resident immune cells into our models enables us to detect side effects that cannot be detected by conventional systems.
If you have specific requirements, please do not hesitate to contact us. Our experienced scientists will tailor your project for you to address your scientific questions in such a way that you receive the required information cost-effectively and promptly.