Immunocompetence & Infection models
Vascularization & Organ-specific perfusion
Multi-organ models
Biochips with low compound adsorption
Scalable complexity
Low investment cost & Easy handling/integration
Organ-on-chip is a technology that reproduces the biology of human organs on a biochip on a small scale. Such organ models reproduce key functions and physiological responses of human organs and tissues, providing human-relevant data for preclinical drug testing and biomedical research.
Find out more about how organ-on-chip technology is shaping the future of clinical research:
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Create in vitro human disease and infection models with our DynamicOrgan system. Our system enables physiological cell and tissue culture to help you reproduce all our standard organ models or build completely new ones. With the DynamicOrgan system you can reproduce key organ functions, including the vasculature, immune cells, microbiome and pathogens. The system components, such as our biochips and pump, integrate seamlessly into your existing workflows, are easy to use and don’t require capital expenditure.
You can use our services for toxicology screenings, lead identification and optimization, as well as in vitro model development. Our unique immune-competent organ models enable you to gain deeper understanding of human cellular biology in health and disease. It can help you to strengthen your pre-clinical data set, to perform target validation, to investigate molecular mechanisms and to prioritize further developments.
Learn about who we are through our mission and vision:
Get quarterly organ-on-chip insights and news to stay up-to-date with the field:
BASF
Sanofi
Bayer’s Consumer Health Division
Leibniz Institute for Natural Product Research and Infection Biology (Leibniz-HKI)
Jena University Hospital
Freie Universität Berlin
HZI Braunschweig
MLU Halle-Wittenberg
Dynamic42 and Heinrich Heine University have developed a tumour-on-a-chip model that replicates the microenvironment of pancreatic ductal adenocarcinoma (PDAC). This 3D model allows for realistic drug testing and could accelerate the development of personalized therapies.
Read MoreDynamic42, in collaboration with ESQlabs, Bayer, and the Placenta Lab, has developed an innovative three-organ system with the potential to reduce animal testing in pharmaceutical research.
Read MoreWe were interviewed by the Ostthüringer Zeitung on the subject of animal-free research.
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