Blog

Learn in this blog how Valentin Wegner uses a gut-on-chip model to understand how SCFAs regulate the efficacy of CAR T cell function.

This blog lists examples of organ-on-chip models by organ type that have been used in the past, providing the respective literature for your reference.

This guest blog by Viraj Mehta proposes a classification system categorizing organ-on-chip technologies based on design and functionality, thus facilitating clearer regulatory guidelines, fostering innovation, and improving educational resources.

This blog explores established infection models using our organ-on-chip technology and their implications for scientific research.

One crucial factor that plays a pivotal role in the success of organ-on-cip models is immunocompetence. In this blog post, we delve into the significance of immunocompetence in organ-on-chip models and how it opens new avenues for advancing medical research.

Brief summary on our work focusing on the development of a sophisticated intestine-on-chip model to study fungal infections, particularly candidiasis.

One crucial factor that plays a pivotal role in the success of organ-on-cip models is immunocompetence. In this blog post, we delve into the significance of immunocompetence in organ-on-chip models and how it opens new avenues for advancing medical research.

Learn the skills to integrate organ-on-chip technology into your lab work with the Dynamic42 Academy. If this resonates with you, this blog will help you to understand if our organ-on-chip class is for you. We will give you a deep dive into the reasons to attend our course, what we teach in the course, and what past participants have to say.

A comprehensive summary of available organ-on-chip courses, detailing the provider, content and location. Organ-on-chip technology is an amazing technique to model human, physiological mechanisms on a small scale without the use of animal models. If you as a researcher are versed in cell culture, learning how to create your own organ models is absolutely feasible in just a few months.

We look back on 2023 – from significant milestones, groundbreaking developments and trusting partnerships to new faces in our team. We’ll take you with us as we review the past year.

In this article, we will discuss common issues observed when working with biochips made of PDMS, most commonly used alternatives, and desired properties for biochip materials. But most importantly, we will present alternative biochips showing low adsorptions rates but also unique biocompatibility for high grade drug screening.

In this blog we will provide you with an introduction to the drug development process from target validation to post-market surveillance to give you a better understanding on how new drugs are being developed.

As an expert in business development, Georg enriches our team at Dynamic42. With his creative approach and many years of experience in medical technology and project management, Georg is a valuable addition to our team.

Organ-on-Chip technology (OoC) has the potential to shape the future of drug research. It allows the simulation of human organs on a chip, enabling more reliable tests for drug development.

Summary of our work that established a human liver microphysiological model as an in vitro platform for the evaluation of drug-induced liver injury, published in Nature Scientific Reports. This case study sheds light on the effects of the known hepatotoxic antibiotic trovafloxacin and the commonly used analog levofloxacin on human liver tissue, using an innovative chip-based liver model.

Lately Thomas Sommermann joined Dynamic42. Thomas is an experienced scientist in the field of immunology and shares our vision regarding the enormous potential of the organ-on-chip technology.

In April, our CEO Martin Raasch and our scientists Anne-Katrin Bothe and Tim Kaden attended the 3D Cell Culture Conference in Freiburg.

Dynamic42 is one of the chosen companies and research groups receiving funding from of the Sanofi iDEA-iTECH Award.

Dynamic42 GmbH is celebrating its fifth anniversary this spring. The last few years have been characterised by continuous growth, professionalisation and forward-looking innovations.

Science is our passion. That’s why we invest in the next generation of scientists. Meet our Master’s students Sophie and Daria.

With the help of organ models, we are already increasing drug safety and advancing approaches for individualized medicine.

Meet our Lab Manager Katja Graf: I am proud to be involved in developing and commercializing a pioneering technology such as organ-on-chip.

Senior Scientist Dr. Rizwan Rehimi joined Dynamic42 for a joint project with the Institute of Pharmaceutical Biology and Biotechnology at Heinrich Heine University.

With the registration of Dynamic42 as a trademark, we are setting an example in the direction of future viability and growth.

We recently celebrated our fourth company birthday. Time to look back and at the same time look forward with excitement to new developments.

We are looking forward to two new colleagues for our research and laboratory team!

At MEDICA, our Managing Director Dr. Martin Raasch presented a microphysiological lung model with integrated immune cells, which we have been working on since 2017.

The award underlines that we guarantee high quality standards in the development, production, and distribution of biochips as well as in the services of organ-on-chip models.

With our organ-on-chip platform, chemical and toxicological tests can be carried out on human cell cultures.

2021: Three years ago we started with Dynamic42! We look back on a successful time that was characterized by growth. Learn more about us!

From August 23 to September 2, 2021, the online conference WC11 took place under the motto “3Rs in Transition: From Development to Application”. We report to you from the conference.

We want to take the plunge across the pond! We participated in the intensive workshop Step USA Virtual. It is a very successful!

Congratulations to our managing director Dr. Martin Raasch!

We were happy that Dynamic42 received one of the coveted lecture places. Our managing directors presented Dynamic42 GmbH in a pitch. We were also represented with our digital trade fair stand in the Innovation Arena.

From May 5 to May 7, 2021, the online conference 3D Cell Culture took place around the latest scientific findings and current model innovations in the fields of synthetic biology, tumor research, 3D models and microphysiological systems. We were there!

Organ-on-chip technology provides efficient and ethical methods for food and drug testing.

For Dynamic42, the biotech laboratory is the most important workplace. Attending to the World Laboratory Day, we would like to give you exclusive insights into our workplace.

2020 was characterized by growth. We closed a seven-digit financing round and expanded our team.

What does it mean to work with organ-on-chip? What is 3R? Where are the opportunities and benefits for understanding human cellular mechanisms, modeling human diseases, and screening drugs?