Explore human biology with immunocompetent organ models of true physiological complexity

Our organ models will support your vision of human-relevant research, for better clinical outcomes and disease insights that matter, while minimizing the impact on animals.

Immunocompetence & Infection models

Vascularization & Organ-specific perfusion

Multi-organ models

Biochips with low compound adsorption

Scalable complexity

Low investment cost & Easy handling/integration

What is Organ-on-chip-technology? 

Organ-on-chip is a technology that reproduces the biology of human organs on a biochip on a small scale. Such organ models reproduce key functions and physiological responses of human organs and tissues, providing human-relevant data for preclinical drug testing and biomedical research.

 

Find out more about how organ-on-chip technology is shaping the future of clinical research:

 

More about our Technology

Our Immunocompetent Organ-on-Chip Models

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Our Products & Services

Build your own organ models

Create in vitro human disease and infection models with our DynamicOrgan system. Our system enables physiological cell and tissue culture to help you reproduce all our standard organ models or build completely new ones. With the DynamicOrgan system you can reproduce key organ functions, including the vasculature, immune cells, microbiome and pathogens. The system components, such as our biochips and pump, integrate seamlessly into your existing workflows, are easy to use and don’t require capital expenditure.

More about the DynamicOrgan System

Contract Research Services

You can use our services for toxicology screenings, lead identification and optimization, as well as in vitro model development. Our unique immune-competent organ models enable you to gain deeper understanding of human cellular biology in health and disease. It can help you to strengthen your pre-clinical data set, to perform target validation, to investigate molecular mechanisms and to prioritize further developments.

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Company

Learn about who we are through our mission and vision:

Organ-on-Chip news

Get quarterly organ-on-chip insights and news to stay up-to-date with the field:

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Our Customers

BASF

Sanofi

Bayer’s Consumer Health Division

Leibniz Institute for Natural Product Research and Infection Biology (Leibniz-HKI)

Jena University Hospital

Frei Universität Berlin 

HZI Braunschweig

MLU Hallo-Wittenberg

News

News

Improving people's lives with innovative technologies. This was the goal that Jena-based Dynamic42 had in mind 18 months ago when they launched a project - funded as part of the Sanofi iDEA-iTECH Award Program.

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News

The RUBIN alliance “ATHANA” met for their first strategy workshop one year after the project kicked off in summer last year.

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News

We are excited to welcome Amélie Marie Paillereau to the Dynamic42 science team. Amélie started in April with us for a 12-month-long Master thesis, focusing on perfused breast and pancreatic cancer-on-chip models to study the impact of the tumor microenvironment on immune cell invasion.

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