The faces of Dynamic42: Thomas Sommermann
Lately Thomas Sommermann joined Dynamic42. Thomas is an experienced scientist in the field of immunology and shares our vision regarding the enormous potential of the organ-on-chip technology. Therefore, we are very happy to have him support our research team!
From Nuremberg to Jena via Cambridge and Berlin
Thomas joins us from the Hans Knöll Institute (HKI), where he was a senior postdoc and head of the cell sorting facility at the Infection Immunology department of Professor C. Zielinski. In his role he performed spectral, high-dimensional FACS (Fluorescence Activated Cell Sorter) analyses and sorting of immune cells especially human T cells.
Thomas began his carrier at the Friedrich-Alexander University of Nuremberg-Erlangen, where he studied biology with a focus on molecular cell biology in the field of colorectal cancer.
After successfully completing his diploma, he was offered a PhD-student fellowship at Harvard University in Cambridge, USA. In his PhD work Thomas addressed cell signaling and cell metabolism of lymphomas associated with Epstein-Barr virus.
Thomas’ then joined the department of Immune Regulation and Cancer at the Max Delbrück Center in Berlin. There he continued his research on lymphomas and the Epstein-Barr virus using transgenic mouse models.
Diversification of immune cell types: Thomas’ goals at Dynamic42
Having worked extensively with mouse models, Thomas is sure that there are limitations to translating findings from animal research into the human system, creating a fundamental need to develop novel complementary and alternative methods to animal testing.
``I strongly believe that organ chip technology has the potential to provide more reliable preclinical data than current animal-based experiments.``
Thomas will now promote the efforts of Dynamic42 to further integrate various immune cell populations into organ-chips. Immunocompetent organ models better mimic real body physiology and will allow D42 to address the effects of treatment approaches on immune cells within the target tissue.
More interesting articles:
Blog, Organ-on-Chip Technology
Debunking 6 common misconceptions about organ-on-chip technology
In this blog we explore common misconceptions around Organ-on-chip technology that lead to false expectations or unnecessary skepticism. Our scientists at Dynamic42 set the record straight.
Read MoreBlog, Organ-on-Chip Technology
Advantages and Limitations of Organ‑on‑Chip Technology
Like any emerging technology, OoC systems come with limitations and challenges. In this article, we’ll explore both sides: why researchers are enthusiastic about OoCs, and where the technology still falls short.
Read MoreBlog, Organ-on-Chip Technology, TEER Sensors
Beyond endpoints – Real-time insights into barrier dynamics with TEER in organ-on-chip
This blog compares different methods for assessing barrier permeability in OoC models addressing limitations of traditional endpoint assays.
Read More

